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Actoplus Met XR and Edema

Result of checking the interaction of drug Actoplus Met XR and disease Edema for safety when used together.

Check result:

Actoplus Met XR <> Edema

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Thiazolidinediones can cause dose-related edema. Therapy with thiazolidinediones should be administered cautiously in patients at risk for congestive heart failure as well as those with fluid overload or other conditions that may be adversely affected by excess fluid such as hypertension. Patients should be monitored for signs and symptoms of heart failure such as dyspnea, swelling of legs or ankles, and weight gain.

References:

"Product Information. Rezulin (troglitazone)." Parke-Davis, Morris Plains, NJ.
"Product Information. Actos (pioglitazone)" Takeda Pharmaceuticals America, Lincolnshire, IL.
Thomas ML, Lloyd SJ "Pulmonary edema associated with rosiglitazone and troglitazone." Ann Pharmacother 35 (2001): 123-4
"Product Information. Avandia (rosiglitazone)" SmithKline Beecham, Philadelphia, PA.

Actoplus Met XR

Generic Name: metformin / pioglitazone

Brand Name: Actoplus Met, Actoplus Met XR

Synonyms: n.a.

What is Actoplus Met XR?