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Actonel with Calcium and Renal dysfunction

Result of checking the interaction of drug Actonel with Calcium and disease Renal dysfunction for safety when used together.

Check result:
Actonel with Calcium <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Absorption of oral calcium formulations may be altered and elimination of calcium by the kidney decreased with renal impairment. Hyperphosphatemia occurs during renal failure. Calcium acetate or calcium carbonate, in addition to providing calcium, complexes phosphates within the GI tract. Calcium carbonate can partially correct metabolic acidosis associated with chronic renal failure. Clinical monitoring of renal function and serum calcium and phosphate concentrations is necessary.

References:
  • "Product Information. Neo-Calglucon (calcium glubionate)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • "Product Information. Posture (calcium phosphate, triphasic)." Whitehall-Robbins, Madison, NJ.
Actonel with Calcium

Generic Name: calcium carbonate / risedronate

Brand Name: Actonel with Calcium, Actonel and Calcium

Synonyms: n.a.

What is Actonel with Calcium?
Another drug Delete
Actonel with Calcium <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Risedronate is primarily eliminated by the kidney. The renal clearance of the drug is decreased in patients with impaired renal function. Risedronate is not recommended for use in patients with creatinine clearance less than 30 mL/min due to a lack of clinical experience in this setting. No dosage adjustment is necessary in patients with mild to moderate renal impairment (CrCl >= 30 mL/min).

References:
  • "Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
  • Mitchell DY, Eusebio RA, SaccoGibson NA, Pallone KA, Kelly SC, Nesbitt JD, Brezovic CP, Thompson GA, Powell JH "Dose-proportional pharmacokinetics of risedronate on single-dose oral administration to healthy volunteers." J Clin Pharmacol 40 (2000): 258-65
  • Mitchell DY, StPeter JV, Eusebio RA, Pallone KA, Kelly SC, Russell DA, Nesbitt JD, Thompson GA, Powell JH "Effect of renal function on risedronate pharmacokinetics after a single oral dose." Br J Clin Pharmacol 49 (2000): 215-22
Actonel with Calcium

Generic Name: calcium carbonate / risedronate

Brand Name: Actonel with Calcium, Actonel and Calcium

Synonyms: n.a.

What is Actonel with Calcium?
Another drug Delete
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