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Butalbital, Acetaminophen, and Caffeine Capsules and Tablets and Hematologic toxicity

Result of checking the interaction of drug Butalbital, Acetaminophen, and Caffeine Capsules and Tablets and disease Hematologic toxicity for safety when used together.

Check result:

Butalbital, Acetaminophen, and Caffeine Capsules and Tablets <> Hematologic toxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Hematologic toxicity, including agranulocytosis, thrombocytopenic purpura and megaloblastic anemia, has been reported rarely during use of barbiturates. Therapy with barbiturates should be administered cautiously in patients with preexisting blood dyscrasias or bone marrow suppression. Blood counts are recommended prior to and periodically during long-term therapy, and patients should be instructed to immediately report any signs or symptoms suggestive of blood dyscrasia such as fever, sore throat, local infection, easy bruising, petechiae, bleeding, pallor, dizziness, or jaundice. Barbiturate therapy should be discontinued if blood dyscrasias occur.

References:

Iivanainen M, Savolainen H "Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy." Acta Neurol Scand Suppl 97 (1983): 49-67
"Product Information. Phenobarbital (phenobarbital)." Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Seconal Sodium (secobarbital)" Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Mebaral (mephobarbital)" Sanofi Winthrop Pharmaceuticals, New York, NY.
"Product Information. Amytal Sodium (amobarbital)" Lilly, Eli and Company, Indianapolis, IN.
Van Hoof A, Chamone DA, Vermylen J "Platelet aggregation and anaesthesia." Lancet 2 (1980): 373
"Product Information. Nembutal Sodium (pentobarbital)" Abbott Pharmaceutical, Abbott Park, IL.
Kiorboe E, Plum CM "Megaloblastic anaemia developing during treatment of epilepsy." Acta Med Scand Suppl 445 (1966): 349-57
"Product Information. Butisol Sodium (butabarbital)" Wallace Laboratories, Cranbury, NJ.

Butalbital, Acetaminophen, and Caffeine Capsules and Tablets

Generic Name: acetaminophen / butalbital / caffeine

Brand Name: Capacet, Esgic, Fioricet, Margesic, Medigesic, Orbivan, Repan, Vanatol LQ, Zebutal, Esgic-Plus, Arcet, Isocet, Pharmagesic, Anoquan, Two-Dyne, Tenake, Anolor 300, Femcet, Geone, Tencet, Triad, Fiorpap, Dolmar, Endolor, Ezol, Ide-cet, G-1, Minotal, Mygracet, Pacaps, Alagesic, Americet, Nonbac, Dolgic LQ, Dolgic Plus, Vanatol S, Alagesic LQ

Synonyms: Acetaminophen, butalbital, and caffeine, Butalbital, Acetaminophen, and Caffeine

What is Butalbital, Acetaminophen, and Caffeine Capsules and Tablets?