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Buprenorphine and Naloxone Sublingual Tablets and Septic shock

Result of checking the interaction of drug Buprenorphine and Naloxone Sublingual Tablets and disease Septic shock for safety when used together.

Check result:
Buprenorphine and Naloxone Sublingual Tablets <> Septic shock
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Naloxone has been shown in some cases of septic shock to produce a rise in blood pressure that may last up to several hours; however, this pressor response has not been demonstrated to improve patient survival. In some studies, treatment with naloxone in the setting of septic shock has been associated with adverse effects, including agitation, nausea and vomiting, pulmonary edema, hypotension, cardiac arrhythmias, and seizures. The decision to use naloxone in septic shock should be exercised with caution, particularly in patients who may have underlying pain or have previously received opioid therapy and may have developed opioid tolerance.

Buprenorphine and Naloxone Sublingual Tablets

Generic Name: buprenorphine / naloxone

Brand Name: Bunavail, Suboxone, Zubsolv

Synonyms: Buprenorphine and naloxone (oral/sublingual), Buprenorphine and Naloxone