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Buprenorphine and Naloxone Sublingual Tablets and Gastrointestinal obstruction

Result of checking the interaction of drug Buprenorphine and Naloxone Sublingual Tablets and disease Gastrointestinal obstruction for safety when used together.

Check result:

Buprenorphine and Naloxone Sublingual Tablets <> Gastrointestinal obstruction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with gastrointestinal obstruction, particularly paralytic ileus, should generally not be given sustained-release oral formulations of narcotic analgesics. Opioid agents are is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. In such patients, the ingested drug may remain in the stomach for an extended period of time, then released suddenly as a bolus when normal gut motility is restored, thereby increasing the risk for adverse effects and/or an overdose.

References:

"Product Information. OxyContin (oxycodone)." Purdue Frederick Company, Norwalk, CT.
"Product Information. Kadian (morphine)." Zeneca Pharmaceuticals, Wilmington, DE.

Buprenorphine and Naloxone Sublingual Tablets

Generic Name: buprenorphine / naloxone

Brand Name: Bunavail, Suboxone, Zubsolv

Synonyms: Buprenorphine and naloxone (oral/sublingual), Buprenorphine and Naloxone

What is Buprenorphine and Naloxone Sublingual Tablets?