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Bexarotene (Systemic) and Liver dysfunction

Result of checking the interaction of drug Bexarotene (Systemic) and disease Liver dysfunction for safety when used together.

Check result:

Bexarotene (Systemic) <> Liver dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

In vitro studies suggest that cytochrome P450 3A4 is the major cytochrome P450 responsible for formation of the oxidative metabolites and that the oxidative metabolites may be glucuronidated. It is recommended to monitor for signs of toxicity due to increased drug exposure if bexarotene is used in patients with hepatic impairment as these patients are expected to have a decreased drug clearance.

Bexarotene (Systemic)

Generic Name: bexarotene

Brand Name: Targretin

Synonyms: Bexarotene

What is Bexarotene (Systemic)?