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Acetazolamide Tablets and Severe liver disease

Result of checking the interaction of drug Acetazolamide Tablets and disease Severe liver disease for safety when used together.

Check result:
Acetazolamide Tablets <> Severe liver disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of carbonic anhydrase inhibitors is contraindicated in patients with marked liver disease or cirrhosis. Carbonic anhydrase inhibitors increase the risk of developing hepatic encephalopathy in these patients. Extreme caution should be exercised if carbonic anhydrase inhibitors are administered in patients with mild to moderate liver disease as the clearance of the drug can be decreased. A dose reduction might be needed and monitoring of the liver function is recommended.

References:
  • Margo CE "Acetazolamide and advanced liver disease." Am J Ophthalmol 101 (1986): 611-2
  • "Product Information. Diamox (acetazolamide)." Lederle Laboratories, Wayne, NJ.
  • Maren TH "Acetazolamide and advanced liver disease ." Am J Ophthalmol 102 (1986): 672-3
Acetazolamide Tablets

Generic Name: acetazolamide

Brand Name: Diamox, Diamox Sequels

Synonyms: Acetazolamide, AcetaZOLAMIDE

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