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Acetazolamide Tablets and Respiratory acidosis

Result of checking the interaction of drug Acetazolamide Tablets and disease Respiratory acidosis for safety when used together.

Check result:
Acetazolamide Tablets <> Respiratory acidosis
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Carbonic anhydrase inhibitors may exacerbate pulmonary disease in patients with elevated pCO2 levels. Respiratory acidosis may be precipitated or increased in these patients. Therapy with carbonic anhydrase inhibitors should be administered cautiously in patients with respiratory acidosis, and conditions where alveolar ventilation may be impaired (pulmonary obstruction, emphysema, etc) and can precipitate or aggravate acidosis. Respiratory status should be monitored during therapy.

References:
  • "Product Information. Diamox (acetazolamide)." Lederle Laboratories, Wayne, NJ.
  • Siklos P, Henderson RG "Severe acidosis from acetazolamide in a diabetic patient." Curr Med Res Opin 6 (1979): 284-6
  • Watson WA, Garrelts JC, Zinn PD, Garriott JC, McLemore TL, Clementi WA "Chronic acetazolamide intoxication." J Toxicol Clin Toxicol 22 (1984-85): 549-63
Acetazolamide Tablets

Generic Name: acetazolamide

Brand Name: Diamox, Diamox Sequels

Synonyms: Acetazolamide, AcetaZOLAMIDE

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