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Zyvox (Linezolid Suspension) and Carcinoid syndrome

Result of checking the interaction of drug Zyvox (Linezolid Suspension) and disease Carcinoid syndrome for safety when used together.

Check result:
Zyvox (Linezolid Suspension) <> Carcinoid syndrome
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Linezolid is a weak, reversible, nonselective monoamine oxidase inhibitor (MAOI). Nonspecific MAOIs inhibit the breakdown of pressor amines, including serotonin, and may exacerbate symptoms of the carcinoid syndrome. While adverse effects related to MAOI activity have not been reported with linezolid, the potential for excessive serotonergic effects should be considered. Therapy with linezolid should be administered cautiously in patients with carcinoid syndrome and in patients receiving serotonergic agents. Clinical data are not available concerning the use of linezolid in these populations.

References:
  • "Product Information. Zyvox (linezolid)" Pharmacia and Upjohn, Kalamazoo, MI.
Zyvox (Linezolid Suspension)

Generic Name: linezolid

Brand Name: Zyvox

Synonyms: Zyvox

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