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Zoster Vaccine (Live/Attenuated) and Immunodeficiency

Result of checking the interaction of drug Zoster Vaccine (Live/Attenuated) and disease Immunodeficiency for safety when used together.

Check result:
Zoster Vaccine (Live/Attenuated) <> Immunodeficiency
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

In general, the use of varicella virus vaccine is contraindicated in patients with primary or acquired immunodeficiency or infection with HIV. Since varicella virus vaccine contains live attenuated virus, the absence of immune competence may potentiate the replication of vaccine virus, increase adverse host reactions, and compromise serum antibody response. The vaccine should not be administered to immunosuppressed or immunodeficient individuals and those receiving immunosuppressive therapy, including individuals receiving immunosuppressive doses of corticosteroids as it may cause an extensive vaccine-associated rash or disseminated disease in these individuals.

References:
  • "Product Information. Varivax (varicella virus vaccine live)." Merck & Co, Inc, West Point, PA.
  • American Academy of Pediatrics. Committee on Infectious Diseases; Peter G, ed. "Red BooK: Report of the Committee on Infectious Diseases. 24th" Grove Village, IL: American Academy of Pediatrics (1997):
Zoster Vaccine (Live/Attenuated)

Generic Name: zoster vaccine live

Brand Name: Zostavax

Synonyms: Zoster vaccine live

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