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Baclofen Intrathecal and Renal dysfunction

Result of checking the interaction of drug Baclofen Intrathecal and disease Renal dysfunction for safety when used together.

Check result:

Baclofen Intrathecal <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Baclofen is primarily eliminated by the kidney. Patients with impaired renal function may be at greater risk for adverse effects from baclofen due to decreased drug clearance. Therapy with baclofen should be administered cautiously in such patients. Dosage adjustments may be necessary.

References:

Himmelsbach FA, Kohler E, Zanker B "Toxic effect of baclofen in chronic haemodialysis and renal transplantation." Dtsch Med Wochenschr 117 (1992): 733-7
Krahn A, Penner SB "Use of baclofen for intractable hiccups in uremia." Am J Med 96 (1994): 391
"Product Information. Lioresal (baclofen)." Medtronic Inc, Minneapolis, MN.

Baclofen Intrathecal

Generic Name: baclofen

Brand Name: Lioresal Intrathecal, Gablofen, FIRST Baclofen, Lioresal, Ozobax

Synonyms: Baclofen

What is Baclofen Intrathecal?