Drug search by name

Zolpidem Sublingual Tablets (Intermezzo) and Renal dysfunction

Result of checking the interaction of drug Zolpidem Sublingual Tablets (Intermezzo) and disease Renal dysfunction for safety when used together.

Check result:

Zolpidem Sublingual Tablets (Intermezzo) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Zolpidem is extensively metabolized by the liver and subsequently excreted in the urine, primarily as metabolites. Limited data suggest that the pharmacokinetic disposition of zolpidem is not altered in the presence of renal insufficiency or even end-stage renal disease, and that there is no accumulation of unchanged drug after repeated dosing. However, the effects of possible metabolite accumulation have not been studied. While dosage adjustments are generally not required, close monitoring is recommended in patients with impaired renal function treated with zolpidem.

References:

"Product Information. Ambien (zolpidem)." sanofi-aventis, Bridgewater, NJ.
Langtry HD, Benfield P "Zolpidem. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential." Drugs 40 (1990): 291-313

Zolpidem Sublingual Tablets (Intermezzo)

Generic Name: zolpidem

Brand Name: Ambien, Ambien CR, Edluar, Intermezzo, ZolpiMist

Synonyms: Zolpidem

What is Zolpidem Sublingual Tablets (Intermezzo)?