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Zolate and Anemia

Result of checking the interaction of drug Zolate and disease Anemia for safety when used together.

Check result:
Zolate <> Anemia
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of folic acid is contraindicated in patients with undiagnosed anemia. Folic acid in dosages above 1 mg/day can obscure the diagnosis of pernicious anemia by alleviating the hematologic abnormalities while allowing the progression of neurologic complications. In addition, folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.

References:
  • Butterworth CE Jr, Tamura T "Folic acid safety and toxicity: a brief review." Am J Clin Nutr 50 (1989): 353-8
  • Katz M "Potential danger of self-medication with folic acid." N Engl J Med 289 (1973): 1095
  • "Product Information. Renal Multivitamin Formula Rx (folic acid)." Vitaline Corporation, Ashland, OR.
Zolate

Generic Name: cholecalciferol / folic acid

Brand Name: Ortho D, Zolate, Ortho DF, Genicin Vita-D

Synonyms: n.a.

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