Drug search by name

Zoladex (Goserelin Implant 10.8 mg) and Bone mineral density

Generic Name: goserelin
Dosage Forms: implant
Other Brand Names: Zoladex

Result of checking the interaction of drug Zoladex (Goserelin Implant 10.8 mg) and disease Bone mineral density for safety when used together.

Check result:

Zoladex (Goserelin Implant 10.8 mg) <> Bone mineral density

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of GnRH agonists in women may cause a reduction in bone mineral density. In women, current available data suggest that recovery of bone loss occurs on cessation of therapy in the majority of patients. Postmarketing data has also shown osteoporosis, decreased bone mineral density and bone fracture in men. Therapy with goserelin should be administered cautiously in patients with major risk factors for decreased bone mineral content, such as chronic alcohol and/or tobacco use, a strong family history of osteoporosis, or chronic use of drugs that can reduce bone mass (e.g., anticonvulsants, corticosteroids).

References: