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Zidovudine Intravenous and Renal dysfunction

Result of checking the interaction of drug Zidovudine Intravenous and disease Renal dysfunction for safety when used together.

Check result:

Zidovudine Intravenous <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with clinically significant renal impairment may be at greater risk for toxicities and adverse effects from nucleoside reverse transcriptase inhibitors (NRTIs) due to decreased drug clearance. Dosage adjustments are recommended. In addition, these patients should be monitored closely during NRTI therapy, and dosages adjusted further if necessary.

References:

"Product Information. HIVID (zalcitabine)." Roche Laboratories, Nutley, NJ.
"Product Information. Retrovir (zidovudine)." Glaxo Wellcome, Research Triangle Park, NC.
"Product Information. Zerit (stavudine)." Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Epivir (lamivudine)." Glaxo Wellcome, Research Triangle Park, NC.

Zidovudine Intravenous

Generic Name: zidovudine

Brand Name: Retrovir

Synonyms: Zidovudine (oral/injection), Zidovudine

What is Zidovudine Intravenous?