Xyrem and Hx drug/alcohol abuse
Result of checking the interaction of drug Xyrem and disease Hx drug/alcohol abuse for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Sodium oxybate should not be used with alcohol. This drug should be used with caution in patients with history of drug or alcohol abuse. The inappropriate use of this drug alone or in combination with other CNS depressants is associated with CNS adverse reaction including seizures, respiratory depression, decreases in the levels of consciousness, coma and death. Because illicit use and abuse has been reported, physicians should evaluate carefully their patients for history of drug or alcohol abuse and should follow such patients closely, observing them for signs of misuse.