Drug search by name

Xtampza ER and Arrhythmias

Result of checking the interaction of drug Xtampza ER and disease Arrhythmias for safety when used together.

Check result:

Xtampza ER <> Arrhythmias

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Opiate agonists have cholinergic activity. Large doses and/or rapid intravenous administration may produce bradycardia and arrhythmia via stimulation of medullary vagal nuclei. Unlike other agents in the class, meperidine also has anticholinergic activity and may cause either bradycardia or tachycardia. Therapy with opiate agonists should be administered cautiously in patients with a history of arrhythmias. Clinical monitoring of cardiovascular status is recommended during therapy. Bradycardia and other cholinergic effects produced by these agents may be controlled with atropine.

References:

"Product Information. Opium Tincture (opium)" Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Duragesic Transdermal System (fentanyl)." Janssen Pharmaceutica, Titusville, NJ.
"Product Information. Darvon (propoxyphene)." Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Alfenta (alfentanil)." Janssen Pharmaceutica, Titusville, NJ.
"Product Information. MS Contin (morphine)." Purdue Frederick Company, Norwalk, CT.
Blair JR, Pruett JK, Crumrine RS, Balser JJ "Prolongation of QT interval in association with the administration of large doses of opiates." Anesthesiology 67 (1987): 442-3
"Product Information. Kadian (morphine)." Zeneca Pharmaceuticals, Wilmington, DE.
"Product Information. Sufenta (sufentanil)." Janssen Pharmaceutica, Titusville, NJ.
"Product Information. Levo-Dromoran (levorphanol)." Roche Laboratories, Nutley, NJ.
"Product Information. Vicoprofen (hydrocodone-ibuprofen)." Knoll Pharmaceutical Company, Whippany, NJ.
"Product Information. Dilaudid (hydromorphone)." Knoll Pharmaceutical Company, Whippany, NJ.
"Product Information. Calcidrine (codeine)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Numorphan (oxymorphone)" Endo Laboratories LLC, Chadds Ford, PA.
Heaney RM "Left bundle branch block associated with propoxyphene hydrochloride poisoning." Ann Emerg Med 12 (1983): 780-2
"Product Information. OxyContin (oxycodone)." Purdue Frederick Company, Norwalk, CT.
"Product Information. Dolophine (methadone)." Lilly, Eli and Company, Indianapolis, IN.
Sebel PS, Bovill JG, Boekhorst RA, Rog N "Cardiovascular effects of high-dose fentanyl anaesthesia." Acta Anaesthesiol Scand 26 (1982): 308-15
Hilgenberg JC, Johantgen WC "Bradycardia after intravenous fentanyl during subarachnoid anesthesia." Anesth Analg 59 (1980): 162-3
"Product Information. Ultiva (remifentanil)." Mylan Institutional (formally Bioniche Pharma USA Inc), Canonsburg, PA.
"Product Information. Sublimaze (fentanyl)." Janssen Pharmaceutica, Titusville, NJ.
"Product Information. Demerol (meperidine)." Sanofi Winthrop Pharmaceuticals, New York, NY.

Xtampza ER

Generic Name: oxycodone

Brand Name: Oxaydo, Oxycontin, Oxyfast, Roxicodone, Xtampza ER, Oxecta, Oxycontin, Roxybond, Xtampza ER; oxycodone is also present in the following combination drugs: Combunox, Endocet, Endodan, Moxduo, Oxycodan, Percocet, Percodan, Primlev, Roxicet, Xartemis XR, and others, OxyIR, Roxybond

Synonyms: n.a.

What is Xtampza ER?