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Xalkori and Bradycardia

Result of checking the interaction of drug Xalkori and disease Bradycardia for safety when used together.

Check result:

Xalkori <> Bradycardia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Crizotinib can cause symptomatic bradycardia. It is recommended to monitor heart rate and blood pressure regularly. It might be necessary to withhold crizotinib in cases of symptomatic bradycardia that is not life-threatening until recovery occurs and then resume treatment at an appropriate dose. Permanently discontinue therapy for life-threatening bradycardia due to crizotinib treatment; however, if associated with concomitant medications known to cause bradycardia or hypotension, hold crizotinib until recovery and if concomitant medications can be adjusted or discontinued, restart treatment with crizotinib at 250 mg once daily with frequent monitoring. Close monitoring is recommended.

Xalkori

Generic Name: crizotinib

Brand Name: Xalkori

Synonyms: n.a.

What is Xalkori?