Drug search by name

Visken and Renal dysfunction

Result of checking the interaction of drug Visken and disease Renal dysfunction for safety when used together.

Check result:

Visken <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pindolol is partially eliminated by the kidney. Although renal impairment does not appear to significantly affect the total clearance of the drug, therapy with pindolol should be administered cautiously in patients with poor renal function. Dosage adjustments may be necessary.

References:

"Product Information. Visken (pindolol)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Krause W, Kampf D, Fischer HC "Pharmacokinetics of mepindolol in patients with chronic renal failure." Eur J Clin Pharmacol 27 (1984): 429-33
MacDonald NJ, Grant AC, Rodger RS, Meredith PA, Elliott HL "The effect of renal impairment on the pharmacokinetics and metabolism of bopindolol." Br J Clin Pharmacol 31 (1991): 697-700
Oie S, Levy G "Relationship between renal function and elimination kinetics of pindolol in man." Eur J Clin Pharmacol 9 (1975): 115-6
Ohnhaus EE, Nuesch E, Meier J, Kalberer F "Pharmacokinetics of unlabelled and 14C-labelled pindolol in uraemia." Eur J Clin Pharmacol 7 (1974): 25-9
Lavene D, Weiss YA, Safar ME, et al "Pharmacokinetics and hepatic extraction ratio of pindolol in hypertensive patients with normal and impaired renal function." J Clin Pharmacol 17 (1977): 501-8
Ohnhaus EE, Heidemann H, Meier J, Maurer G "Metabolism of pindolol in patients with renal failure." Eur J Clin Pharmacol 22 (1982): 423-8
Chau NP, Weiss YA, Safar ME, et al "Pindolol availability in hypertensive patients with normal and impaired renal function." Clin Pharmacol Ther 22 (1977): 505-10
Gugler R, Herold W, Dengler HJ "Pharmacokinetics of pindolol in man." Eur J Clin Pharmacol 7 (1974): 17-24

Visken

Generic Name: pindolol

Brand Name: Visken

Synonyms: n.a.

What is Visken?