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Vancocin and Neutropenia

Result of checking the interaction of drug Vancocin and disease Neutropenia for safety when used together.

Check result:

Vancocin <> Neutropenia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Reversible neutropenia has been reported with intravenous use of vancomycin, usually starting one week or more after initiation of therapy or after a total dosage of more than 25 g. Thrombocytopenia and agranulocytosis (granulocytes < 500/mm3) has occurred rarely. Patients with preexisting neutropenia should be monitored closely during vancomycin therapy for further decreases in leukocyte counts, and therapy discontinued if appropriate.

References:

Adrouny A, Meguerditchian S, Koo CH, et al "Agranulocytosis related to vancomycin therapy." Am J Med 81 (1986): 1059-61
Farwell AP, Kendall LG, Vakil RD, Glew RH "Delayed appearance of vancomycin-induced neutropenia in a patient with chronic renal failure." South Med J 77 (1984): 664-5
Mackett RL, Guay DR "Vancomycin-induced neutropenia." Can Med Assoc J 132 (1985): 39-40
Kauffman CA, Severance PJ, Silva J, Huard TK "Neutropenia associated with vancomycin therapy." South Med J 75 (1982): 1131-3
Koo KB, Bachand RL, Chow AW "Vancomycin-induced neutropenia." Drug Intell Clin Pharm 20 (1986): 780-2
Mandl DL, Garrison MW, Palpant SD "Agranulocytosis induced by vancomycin or ticarcillin/clavulanate." Ann Pharmacother 31 (1997): 1321-4
"Product Information. Vancocin (vancomycin)." Lilly, Eli and Company, Indianapolis, IN.

Vancocin

Generic Name: vancomycin

Brand Name: Vancocin, FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, First-Vancomycin 25, First-Vancomycin 50

Synonyms: n.a.

What is Vancocin?