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Vanadom and Drug dependence

Result of checking the interaction of drug Vanadom and disease Drug dependence for safety when used together.

Check result:
Vanadom <> Drug dependence
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Carisoprodol is partially metabolized to meprobamate, a pharmacologically active agent with known addictive potential. According to the manufacturer, abrupt cessation of carisoprodol 100 mg/kg/day (approximately 5 times the recommended daily adult dosage) was associated with mild withdrawal symptoms such as abdominal cramps, insomnia, headache, nausea and chills in some study subjects. In clinical use, psychological dependence and abuse have been rare. Nevertheless, therapy with carisoprodol should be administered cautiously in addiction-prone individuals, such as those with a history of alcohol or substance abuse. It may be prudent to refrain from dispensing large quantities of medication to these patients.

References:
  • Morse RM, Chua L "Carisoprodol dependence: a case report." Am J Drug Alcohol Abuse 5 (1978): 527-30
  • "Product Information. Soma (carisoprodol)." Meda Pharmaceuticals, Somerset, NJ.
  • Elder NC "Abuse of skeletal muscle relaxants." Am Fam Physician 44 (1991): 1223-6
  • Luehr JG, Meyerle KA, Larson EW "Mail-order (veterinary) drug dependence." JAMA 263 (1990): 657
Vanadom

Generic Name: carisoprodol

Brand Name: Soma, Vanadom

Synonyms: Vanadom (Oral)

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