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Axid Pulvules and Renal dysfunction
Result of checking the interaction of drug Axid Pulvules and disease Renal dysfunction for safety when used together.
Check result:
Axid Pulvules <> Renal dysfunction
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Nizatidine and its metabolites are primarily eliminated by the kidney. Although the drug is generally well-tolerated, the daily dosage should be reduced in patients with moderate to severe renal impairment (CrCl < 50 mL/min).
References:
- Aronoff GR, Bergstrom RF, Bopp RJ, Sloan RS, Callaghan JT "Nizatidine disposition in subjects with normal and impaired renal function." Clin Pharmacol Ther 43 (1988): 688-95
- Gladziwa U, Klotz U "Pharmacokinetic optimisation of the treatment of peptic ulcer in patients with renal failure." Clin Pharmacokinet 27 (1994): 393-408
- "Product Information. Axid (nizatidine)." Lilly, Eli and Company, Indianapolis, IN.
Axid Pulvules
Generic Name: nizatidine
Brand Name: Axid, Axid AR, Axid Pulvules
Synonyms: n.a.
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