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Axid Oral Solution and Renal dysfunction

Result of checking the interaction of drug Axid Oral Solution and disease Renal dysfunction for safety when used together.

Check result:
Axid Oral Solution <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Nizatidine and its metabolites are primarily eliminated by the kidney. Although the drug is generally well-tolerated, the daily dosage should be reduced in patients with moderate to severe renal impairment (CrCl < 50 mL/min).

References:
  • Aronoff GR, Bergstrom RF, Bopp RJ, Sloan RS, Callaghan JT "Nizatidine disposition in subjects with normal and impaired renal function." Clin Pharmacol Ther 43 (1988): 688-95
  • Gladziwa U, Klotz U "Pharmacokinetic optimisation of the treatment of peptic ulcer in patients with renal failure." Clin Pharmacokinet 27 (1994): 393-408
  • "Product Information. Axid (nizatidine)." Lilly, Eli and Company, Indianapolis, IN.
Axid Oral Solution

Generic Name: nizatidine

Brand Name: Baciguent, Probiotic Formula, Proferrin-ES

Synonyms: n.a.

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