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Tylenol Allergy Multi-Symptom and Cardiovascular

Result of checking the interaction of drug Tylenol Allergy Multi-Symptom and disease Cardiovascular for safety when used together.

Check result:
Tylenol Allergy Multi-Symptom <> Cardiovascular
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Antihistamines may infrequently cause cardiovascular adverse effects related to their anticholinergic and local anesthetic (quinidine-like) activities. Tachycardia, palpitation, ECG changes, arrhythmias, hypotension, and hypertension have been reported. Although these effects are uncommon and usually limited to overdosage situations, the manufacturers and some clinicians recommend that therapy with antihistamines be administered cautiously in patients with cardiovascular disease, hypertension, and/or hyperthyroidism.

References:
  • "Product Information. Dimetane (brompheniramine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • "Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
  • "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
  • "Product Information. Tavist (clemastine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
  • "Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
  • Smith SJ "Cardiovascular toxicity of antihistamines." Otolaryngol Head Neck Surg 111 Suppl (1994): 348-54
  • "Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.
  • "Product Information. Drixoral (dextromethorphan)." Schering-Plough, Liberty Corner, NJ.
  • Schuller DE, Turkewitz D "Adverse effects of antihistamines." Postgrad Med 79 (1986): 75-86
  • Woosley RL "Cardiac actions of antihistamines." Annu Rev Pharmacol Toxicol 36 (1996): 233-52
  • "Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
  • "Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
  • "Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.
Tylenol Allergy Multi-Symptom

Generic Name: acetaminophen / chlorpheniramine / phenylephrine

Brand Name: Alka-Seltzer Plus Cold, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Dristan Cold Multi Symptom Formula, Robitussin Nighttime Nasal Relief, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion Nighttime, Contac Cold/Flu Day & Night, Coricidin D Cold/Flu/Sinus, Dristan Cold, Medicidin-D, Onset Forte, Robitussin Peak Cold Nasal Relief, Super Cold Tabs, Super Strength Sinadrin, Tylenol Sinus Congestion/Pain, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus

Synonyms: n.a.

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