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Trimethobenzamide Capsules and Reye's syndrome

Result of checking the interaction of drug Trimethobenzamide Capsules and disease Reye's syndrome for safety when used together.

Check result:

Trimethobenzamide Capsules <> Reye's syndrome

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of trimethobenzamide should be avoided in children and adolescents whose signs and symptoms suggest Reye's syndrome. The extrapyramidal symptoms which can occur secondary to trimethobenzamide use may confound the diagnosis of Reye's syndrome. In addition, drugs with hepatotoxic potential such as trimethobenzamide may adversely affect the course of Reye's syndrome.

References:

"Product Information. Tigan (trimethobenzamide)." Monarch Pharmaceuticals Inc, Bristol, TN.
Holmes C, Flaherty RJ "Trimethobenzamide HCL (Tigan)-induced extrapyramidal dysfunction in a neonate." J Pediatr 89 (1976): 669-70

Trimethobenzamide Capsules

Generic Name: trimethobenzamide

Brand Name: Benzacot, Ticon, Tigan

Synonyms: Trimethobenzamide (oral/injection), Trimethobenzamide

What is Trimethobenzamide Capsules?