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Tridione and Renal dysfunction

Result of checking the interaction of drug Tridione and disease Renal dysfunction for safety when used together.

Check result:

Tridione <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Fatal nephrosis has been associated with the use of oxazolidinedione anticonvulsants. In addition, the active metabolites of these agents are excreted slowly by the kidney and may accumulate in the presence of renal disease. Therapy with oxazolidinediones should be administered cautiously, if at all, in patients with impaired renal function. Urinalyses should be performed in all patients prior to initiating therapy and at monthly intervals, or as often as necessary, thereafter. The development of persistent or increasing albuminuria or any other significant renal abnormality is indication for withdrawal of oxazolidinedione therapy.

References:

"Product Information. Paradione (paramethadione)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Tridione (trimethadione)" Abbott Pharmaceutical, Abbott Part, IL.

Tridione

Generic Name: trimethadione

Brand Name: Tridione

Synonyms: n.a.

What is Tridione?