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Avibactam and cefTAZidime and Renal impairment

Result of checking the interaction of drug Avibactam and cefTAZidime and disease Renal impairment for safety when used together.

Check result:
Avibactam and cefTAZidime <> Renal impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Decreased clinical response has been observed in adult patients treated with the combination product, ceftazidime and avibactam for complicated intra-abdominal infections (cIAI) with baseline creatinine clearance (CrCl) of 30 to less than or equal to 50 mL/min. The decreased clinical response is not observed for patients with moderate renal impairment at baseline (CrCl of 30 to less than or equal to 50 mL/min). It is recommended to monitor CrCl at least daily in adult and pediatric patients with changing renal function and adjust the dosage of treatment according to manufacturer recommendations.

Avibactam and cefTAZidime

Generic Name: avibactam / ceftazidime

Brand Name: Avycaz

Synonyms: Ceftazidime and Avibactam

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