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Trazodone Hydrochloride and Mania

Result of checking the interaction of drug Trazodone Hydrochloride and disease Mania for safety when used together.

Check result:
Trazodone Hydrochloride <> Mania
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

All antidepressants may occasionally cause mania or hypomania, particularly in patients with bipolar disorder. Therapy with antidepressants should be administered cautiously in patients with a history of mania/hypomania.

References:
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  • "Product Information. Desyrel (trazodone)." Bristol-Myers Squibb, Princeton, NJ.
  • Jabeen S, Fisher CJ "Trazodone-induced transient hypomanic symptoms and their management." Br J Psychiatry 158 (1991): 275-8
  • Schweizer E, Weise C, Clary C, Fox I, Rickels K "Placebo-controlled trial of venlafaxine for the treatment of major depression." J Clin Psychopharmacol 11 (1991): 233-6
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  • Dubin H, Spier S, Giannandrea P "Nefazodone-induced mania." Am J Psychiatry 154 (1997): 578-9
  • "Product Information. Serzone (nefazodone)." Bristol-Myers Squibb, Princeton, NJ.
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  • "Product Information. Remeron (mirtazapine)." Organon, West Orange, NJ.
  • Warren M, Bick PA "Two case reports of trazodone-induced mania." Am J Psychiatry 141 (1984): 1103-4
  • Theilman SB, Christenbury MM "Hypomania following withdrawal of trazodone." Am J Psychiatry 143 (1986): 1482-3
  • Montgomery SA "Safety of mirtazapine: a review." Int Clin Psychopharmacol 10(suppl 4 (1995): 37-45
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  • "Product Information. Effexor (venlafaxine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
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Trazodone Hydrochloride

Generic Name: trazodone

Brand Name: Desyrel, Desyrel Dividose, Oleptro

Synonyms: Trazodone, TraZODone

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