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Tranylcypromine and Schizophrenia/bipolar

Result of checking the interaction of drug Tranylcypromine and disease Schizophrenia/bipolar for safety when used together.

Check result:
Tranylcypromine <> Schizophrenia/bipolar
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Monoamine oxidase inhibitor (MAOI) antidepressants may cause excessive stimulation in hyperactive or schizophrenic patients. Symptoms of psychosis may be aggravated in schizophrenia, particularly that with paranoid symptomatology. Depressed patients, usually those with bipolar disorder, may experience a switch from depression to mania or hypomania. Therapy with MAOI antidepressants should be administered cautiously in patients with hyperactive or hyperexcitable personalities, schizophrenia or bipolar disorder.

References:
  • "Product Information. Parnate (tranylcypromine)." SmithKline Beecham, Philadelphia, PA.
  • "Product Information. Nardil (phenelzine)." Parke-Dvis, Morris Plains, NJ.
  • "Product Information. Marplan (isocarboxazid)" Roche Laboratories, Nutley, NJ.
Tranylcypromine

Generic Name: tranylcypromine

Brand Name: Parnate

Synonyms: n.a.

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