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Tranexamic acid and Color vision defect

Result of checking the interaction of drug Tranexamic acid and disease Color vision defect for safety when used together.

Check result:
Tranexamic acid <> Color vision defect
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of tranexamic acid is contraindicated in patients with acquired defective color vision, since this situation precludes the use of one of the ophthalmologic testing parameters as an indicator of drug toxicity. Poorly characterized visual abnormalities have been reported in patients during tranexamic acid therapy. Retinal degeneration in a variety of animal species (not human) at oral and IV doses 3 to 40 times the recommended human dosage has been noted. Ophthalmologic testing (visual acuity, color vision, eyeground, and visual fields) prior to and at regular intervals during treatment is recommended for patients treated longer than several days.

References:
  • "Product Information. Cyklokapron (tranexamic acid)." Pharmacia and Upjohn, Kalamazoo, MI.
Tranexamic acid

Generic Name: tranexamic acid

Brand Name: Cyklokapron, Lysteda

Synonyms: Tranexamic Acid

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