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Trandolapril and verapamil and Neuromuscular transmission

Result of checking the interaction of drug Trandolapril and verapamil and disease Neuromuscular transmission for safety when used together.

Check result:
Trandolapril and verapamil <> Neuromuscular transmission
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Verapamil has been reported to decrease neuromuscular transmission in patients with Duchenne's muscular dystrophy and to prolong recovery from the neuromuscular blocking agent, vecuronium. Therapy with verapamil should be administered cautiously in patients with attenuated neuromuscular transmission or myopathy, since these conditions may be exacerbated. A reduced dosage may be appropriate.

References:
  • "Product Information. Calan (verapamil)." Searle, Skokie, IL.
  • "Product Information. Isoptin (verapamil)." Knoll Pharmaceutical Company, Whippany, NJ.
  • Reverte M "Adverse effect of verapamil in myasthenia gravis: an additional comment." Muscle Nerve 16 (1993): 879-81
Trandolapril and verapamil

Generic Name: trandolapril / verapamil

Brand Name: Tarka

Synonyms: Trandolapril and Verapamil

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