Trametinib Dimethyl Sulfoxide and Hepatic impairment
Result of checking the interaction of drug Trametinib Dimethyl Sulfoxide and disease Hepatic impairment for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Based on a population pharmacokinetic analysis of trametinib, no dose adjustment is recommended in patients with mild hepatic impairment. There are no data on the pharmacokinetics of trametinib in patients with moderate or severe hepatic impairment. Close monitoring is recommended for these patients.
Generic Name: trametinib
Brand Name: Mekinist
Synonyms: Trametinib