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Tramadol and acetaminophen and Acute alcohol intoxication

Result of checking the interaction of drug Tramadol and acetaminophen and disease Acute alcohol intoxication for safety when used together.

Check result:
Tramadol and acetaminophen <> Acute alcohol intoxication
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of tramadol is contraindicated in patients with acute alcohol intoxication exhibiting depressed vital signs. The central nervous system depressant effects of tramadol may be additive with those of alcohol. Severe respiratory depression and death may occur. Therapy with tramadol should be administered cautiously in patients who might be prone to acute alcohol intake. Naloxone may only partially reverse clinically significant tramadol- induced respiratory depression while increasing the risk of tramadol- associated seizures.

References:
  • "Product Information. Ultram (tramadol)." McNeil Pharmaceutical, Raritan, NJ.
  • Kahn LH, Alderfer RJ, Graham DJ "Seizures reported with tramadol." JAMA 278 (1997): 1661
Tramadol and acetaminophen

Generic Name: acetaminophen / tramadol

Brand Name: Ultracet

Synonyms: Acetaminophen and tramadol, Acetaminophen and Tramadol

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