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Tindamax and Liver disease

Result of checking the interaction of drug Tindamax and disease Liver disease for safety when used together.

Check result:

Tindamax <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

There are no data on the pharmacokinetics of tinidazole in patients with impaired hepatic function. Reduction of metabolic elimination of metronidazole, a chemically-related drug, has been reported in patients with hepatic dysfunction. Since tinidazole is also extensively metabolized by the liver prior to excretion, therapy with tinidazole should be administered cautiously in the presence of severe liver disease.

References:

Wood BA, Faulkner JK, Monro AM "The pharmacokinetics, metabolism and tissue distribution of tinidazole." J Antimicrob Chemother 10 Suppl A (1982): 43-57
"Product Information. Tindamax (tinidazole)." Presutti Laboratories Inc, Arlington Heights, IL.

Tindamax

Generic Name: tinidazole

Brand Name: Tindamax, Fasigyn

Synonyms: n.a.

What is Tindamax?