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Tindamax and Hemodialysis

Result of checking the interaction of drug Tindamax and disease Hemodialysis for safety when used together.

Check result:

Tindamax <> Hemodialysis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Tinidazole is removed by hemodialysis. During a 6-hour hemodialysis session, approximately 43% of the drug present in the body is eliminated, and the half-life is reduced from 12 hours to 4.9 hours. Therefore, on days when dialysis is performed, an additional dose of tinidazole equivalent to one-half the prescribed dose is recommended after the hemodialysis session.

References:

Flouvat BL, Imbert C, Dubois DM, et al. "Pharmacokinetics of tinidazole in chronic renal failure and in patients on haemodialysis." Br J Clin Pharmacol 15 (1983): 735-41
"Product Information. Tindamax (tinidazole)." Presutti Laboratories Inc, Arlington Heights, IL.

Tindamax

Generic Name: tinidazole

Brand Name: Tindamax, Fasigyn

Synonyms: n.a.

What is Tindamax?