Drug search by name

Ticlopidine and Bleeding risks

Result of checking the interaction of drug Ticlopidine and disease Bleeding risks for safety when used together.

Check result:

Ticlopidine <> Bleeding risks

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of ticlopidine is contraindicated in patients with hemostatic disorders such as vascular defect or coagulation dysfunction or active pathological bleeding such as peptic ulcer disease or intracranial hemorrhage. Ticlopidine induces an irreversible inhibition of platelet aggregation resulting in a prolongation of bleeding time.

References:

Page Y, Tardy B, Zeni F, Comtet C, Terrana R, Bertrand JC "Thrombotic thrombocytopenic purpura related to ticlopidine." Lancet 337 (1991): 774-6
"Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc, Palo Alto, CA.
Ellie E, Durrieu C, Besse P, Julien J, Gbipki-Benissan G "Thrombotic thrombocytopenic purpura associated with ticlopidine ." Stroke 23 (1992): 922-3
Bennett CL, Weinberg PD, Rozenberg-Ben-Dror K, Yarnold PR, Kwaan HC, Green D "Thrombotic thrombocytopenic purpura associated with ticlopidine." Ann Intern Med 128 (1998): 541-4
Carlson JA, Maesner JE "Fatal neutropenia and thrombocytopenia associated with ticlopidine." Ann Pharmacother 28 (1994): 1236-8

Ticlopidine

Generic Name: ticlopidine

Brand Name: Ticlid

Synonyms: n.a.

What is Ticlopidine?