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Thiothixene and Breast cancer

Result of checking the interaction of drug Thiothixene and disease Breast cancer for safety when used together.

Check result:
Thiothixene <> Breast cancer
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The chronic use of thiothixene is associated with persistent elevations in prolactin levels. Based on in vitro data, approximately one-third of human breast cancers are thought to be prolactin-dependent. The clinical significance of this observation is unknown. Although disturbances such as galactorrhea, amenorrhea, gynecomastia, and impotence have been reported, the clinical significance of elevated serum prolactin levels is unknown for most patients. Chronic administration of antipsychotic drugs has been associated with mammary tumorigenesis in rodent studies but not in human clinical or epidemiologic studies. Therapy with thiothixene should be administered cautiously in patients with existing or suspected malignancy of the breast.

Thiothixene

Generic Name: thiothixene

Brand Name: Navane

Synonyms: n.a.

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