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Teveten HCT and Renal/liver disease

Generic Name: eprosartan / hydrochlorothiazide
Dosage Forms: tablet
Other Brand Names: Teveten HCT

Result of checking the interaction of drug Teveten HCT and disease Renal/liver disease for safety when used together.

Check result:

Teveten HCT <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Eprosartan is partially metabolized by the liver, and both parent drug and metabolites are eliminated by biliary excretion (90%) as well as by the kidney (7%). Dosage adjustments are not necessary in patients with mild renal impairment unless they are also volume-depleted, in which case therapy should be initiated under medical supervision. Likewise, patients with mild hepatic impairment or biliary obstruction generally do not require a dosage adjustment. However, reduced dosages may be appropriate in patients with severe renal, liver, and/or biliary disease, since the clearance may be decreased and unbound drug increased in these states.

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