Drug search by name

Tenuate and Cardiovascular

Result of checking the interaction of drug Tenuate and disease Cardiovascular for safety when used together.

Check result:

Tenuate <> Cardiovascular

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of amphetamines and amphetamine-like drugs is contraindicated in patients with advanced arteriosclerosis, symptomatic or unstable cardio- or cerebrovascular disease, moderate to severe hypertension, or hyperthyroidism. Like other sympathomimetic amines, amphetamines may cause cardiovascular adverse effects such as palpitation, tachycardia, cardiac arrhythmias, and elevation of blood pressure. Rarely, cardiomyopathy manifested as ventricular hypertrophy and/or congestive heart failure has been reported during chronic amphetamine use. In addition, sudden death has been reported in association with amphetamine therapy at usual dosages in children with structural cardiac abnormalities. In general, amphetamines should not be used in patients with structural cardiac abnormalities. If not otherwise contraindicated, therapy with amphetamines should be administered cautiously in patients with a current or past history of cardiovascular or cerebrovascular disease.

References:

"Product Information. Sanorex (mazindol)" Novartis Pharmaceuticals, East Hanover, NJ.
"Product Information. Fastin (phentermine)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Didrex (benzphetamine)" Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Desoxyn (methamphetamine)" Abbott Pharmaceutical, Abbott Park, IL.
Ayres PR "Amphetamine cardiomyopathy [letter]." Ann Intern Med 98 (1983): 110
Gibbs HR "Diet pills and sudden death." N Engl J Med 318 (1988): 1127
Smith HJ, Roche AH, Jausch MF, Herdson PB "Cardiomyopathy associated with amphetamine administration." Am Heart J 91 (1976): 792-7
Bashour TT "Acute myocardial infarction resulting from amphetamine abuse: a spasm- thrombus interplay." Am Heart J 128 (1994): 1237-9
Douglas A, Douglas JG, Robertson CE, Munro JF "Plasma phentermine levels, weight loss and side-effects." Int J Obes 7 (1983): 591-5
"Product Information. Prelu-2 (phendimetrazine)" Boehringer-Ingelheim, Ridgefield, CT.
"Product Information. Dexedrine (dextroamphetamine)" SmithKline Beecham, Philadelphia, PA.
Ragland AS, Ismail Y, Arsura EL "Myocardial infarction after amphetamine use." Am Heart J 125 (1993): 247-9
Kokkinos J, Levine SR "Possible association of ischemic stroke with phentermine." Stroke 24 (1993): 310-3
"Product Information. Tenuate (diethylpropion)" Aventis Pharmaceuticals, Swiftwater, PA.
"Product Information. Adderall (amphetamine-dextroamphetamine)" Shire Richwood Pharmaceutical Company, Florence, KY.