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Temozolomide Intravenous and Renal impairment

Result of checking the interaction of drug Temozolomide Intravenous and disease Renal impairment for safety when used together.

Check result:

Temozolomide Intravenous <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Temozolomide population pharmacokinetic analysis indicated that creatinine clearance over the range of 36 to 130 mL/min/m2 has no effect on its clearance after oral administration. The pharmacokinetics of temozolomide have not been studied in patients with severely impaired renal function (CrCl <36 mL/min/m2). Caution should be exercised when temozolomide is administered to patients with severe renal impairment. Temozolomide has not been studied in patients on dialysis.

Temozolomide Intravenous

Generic Name: temozolomide

Brand Name: Temodar

Synonyms: Temozolomide

What is Temozolomide Intravenous?