Telavancin Hydrochloride and Renal impairment

• Generic Name: telavancin
• Dosage Forms: n.a.
• Other Brand Names: Vibativ

Treatment of nosocomial pneumonia, including hospital-acquired and ventilator-associated pneumonia, caused by susceptible Staphylococcus aureus (including methicillin-resistant S. aureus [MRSA; also known as oxacillin-resistant S. aureus or ORSA]).

If documented or presumed pathogens also include gram-negative or anaerobic bacteria, concomitant use of an anti-infective active against such bacteria may be clinically indicated.

Manufacturer states reserve telavancin for use when alternative treatments for hospital-acquired or ventilator-associated bacterial pneumonia not suitable.

Skin and Skin Structure Infections

Treatment of complicated skin and skin structure infections caused by susceptible S. aureus (including MRSA), Streptococcus pyogenes (group A β-hemolytic streptococci, GAS), S. agalactiae (group B streptococci, GBS), S. anginosus group (includes S. anginosus, S. intermedius, S. constellatus), or Enterococcus faecalis (vancomycin-susceptible strains only).

If documented or presumed pathogens also include gram-negative or anaerobic bacteria, concomitant use of an anti-infective active against such bacteria may be clinically indicated.