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Tegretol XR and Thyroid function tests

Result of checking the interaction of drug Tegretol XR and disease Thyroid function tests for safety when used together.

Check result:

Tegretol XR <> Thyroid function tests

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Decreased values for thyroid function tests have been observed with carbamazepine administration. One study reported decreased serum levels of T4, FT4, and T3. In that study, TSH concentrations were not significantly altered. Clinicians should be cognizant of these effects when prescribing or administering carbamazepine therapy to patients with thyroid disorders.

References:

Strandjord RE, AAnderud S, Myking OL, Johannessen SI "Influence of carbamazepine on serum thyroxine and triiodothyronine in patients with epilepsy." Acta Neurol Scand 63 (1981): 111-21
Delzompo M, Bocchetta A, Loviselli A, Martino E, Post RM, Ketter TA "Thyroid function during carbamazepine." Biol Psychiatry 36 (1994): 135-6
Isojarvi JI, Airaksinen KE, Repo M, Pakarinen AJ, Salmela P, Myllyla VV "Carbamazepine, serum thyroid hormones and myocardial function in epileptic patients." J Neurol Neurosurg Psychiatry 56 (1993): 710-2
"Product Information. Tegretol (carbamazepine)." Novartis Pharmaceuticals, East Hanover, NJ.

Tegretol XR

Generic Name: carbamazepine

Brand Name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

What is Tegretol XR?