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Tegretol XR and Renal dysfunction

Generic Name: carbamazepine
Dosage Forms: n.a.
Other Brand Names: Carbatrol , Epitol , Equetro , Tegretol , Tegretol XR , Tegretol , Tegretol XR

Result of checking the interaction of drug Tegretol XR and disease Renal dysfunction for safety when used together.

Check result:

Tegretol XR <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Most anticonvulsants are primarily excreted by the kidney. The plasma clearance may be decreased and the half-life prolonged in patients with impaired renal function. Therapy with anticonvulsants should be administered cautiously in patients with significant renal dysfunction. In most cases it is recommended to adjust the dosage in patients with CrCl <50 mL/min to half the usual starting dose and then increase slowly to achieve the desired clinical response. The renal function should be monitored regularly in patients receiving therapy.

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