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Tegretol XR and Anticholinergic effects

Result of checking the interaction of drug Tegretol XR and disease Anticholinergic effects for safety when used together.

Check result:
Tegretol XR <> Anticholinergic effects
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Carbamazepine is structurally related to the tricyclic antidepressants and has shown mild anticholinergic activity. Therapy with carbamazepine should be administered cautiously in patients with conditions that may be exacerbated by anticholinergic activity, such as urinary retention or obstruction and elevated intraocular pressure, especially angle-closure glaucoma, untreated intraocular hypertension, or uncontrolled primary open-angle glaucoma.

References:
  • "Product Information. Tegretol (carbamazepine)." Novartis Pharmaceuticals, East Hanover, NJ.
  • Hockings N, Pall A, Moody J, et al "The effects of age on carbamazepine pharmacokinetics and adverse effects." Br J Clin Pharmacol 22 (1986): 725-8
  • Tormey WP "Mechanisms of carbamazepine-induced antidiuresis." J Neurol Neurosurg Psychiatry 56 (1993): 567
Tegretol XR

Generic Name: carbamazepine

Brand Name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

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