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Atropine and pralidoxime and Renal dysfunction

Result of checking the interaction of drug Atropine and pralidoxime and disease Renal dysfunction for safety when used together.

Check result:
Atropine and pralidoxime <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pralidoxime is eliminated by the kidney. Approximately 80% to 90% of pralidoxime is excreted in the urine as unchanged drug. The serum concentration of pralidoxime is increased in patients with renal impairment. Therapy with pralidoxime should be administered cautiously and dosages reduced in patients with compromised renal function. Clinical monitoring of renal function and muscular activity is recommended.

References:
  • "Product Information. Protopam Chloride (pralidoxime)." Baxter Healthcare Corporation, Deerfield, IL.
Atropine and pralidoxime

Generic Name: atropine / pralidoxime

Brand Name: ATNAA, DuoDote

Synonyms: Atropine and Pralidoxime

What is Atropine and pralidoxime?
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