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Sulfasalazine Tablets and Intestinal obstruction

Result of checking the interaction of drug Sulfasalazine Tablets and disease Intestinal obstruction for safety when used together.

Check result:
Sulfasalazine Tablets <> Intestinal obstruction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of sulfasalazine is contraindicated in patients with intestinal obstruction. Approximately one-third of orally administered sulfasalazine is systemically absorbed from the small intestine, while the majority is metabolized by intestinal bacteria to 5-aminosalicylic acid (5-ASA) that remains in the colonic lumen and gets excreted in the feces.

References:
  • "Product Information. Azulfidine (sulfasalazine)." Pharmacia and Upjohn, Kalamazoo, MI.
Sulfasalazine Tablets

Generic Name: sulfasalazine

Brand Name: Azulfidine, Azulfidine EN-tabs, Sulfazine

Synonyms: Sulfasalazine, SulfaSALAzine

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