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Sorbitol-Mannitol and Fluid expansion

Generic Name: mannitol / sorbitol topical
Dosage Forms: irrigation
Other Brand Names:

Result of checking the interaction of drug Sorbitol-Mannitol and disease Fluid expansion for safety when used together.

Check result:

Sorbitol-Mannitol <> Fluid expansion

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of sorbitol solution for urologic irrigation is contraindicated in patients with anuria. In addition, sorbitol irrigation should be administered cautiously in patients with cardiopulmonary or renal dysfunction. Irrigating fluids may enter the systemic circulation, and absorption of large quantities of fluids containing sorbitol may significantly alter cardiopulmonary and renal dynamics. Before and during the urologic procedure, cardiovascular and renal status should be monitored, particularly if the volume absorbed is expected to produce a substantial expansion of the intravascular fluid (e.g., via opened prostatic veins in transurethral prostatectomies).

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