Drug search by name

Atenolol and chlorthalidone and Renal dysfunction

Result of checking the interaction of drug Atenolol and chlorthalidone and disease Renal dysfunction for safety when used together.

Check result:

Atenolol and chlorthalidone <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Atenolol is eliminated by the kidney. Significant accumulation of the drug occurs in patients with a creatinine clearance below 35 mL/min/1.73 m2. Dosage adjustments are recommended for these patients.

References:

Giang DW, Isaeff DM "Atenolol overdosage in a patient with progressive renal failure." West J Med 145 (1986): 101-3
"Product Information. Tenormin (atenolol)." ICN Pharmaceuticals Inc, Cost Mesa, CA.
Kirch W, Kohler H, Mutschler E, Schafer M "Pharmacokinetics of atenolol in relation to renal function." Eur J Clin Pharmacol 19 (1981): 65-71
Flouvat B, Decourt S, Aubert P, et al. "Pharmacokinetics of atenolol in patients with terminal renal failure and influence of haemodialysis." Br J Clin Pharmacol 9 (1980): 379-85
Sassard J, Pozet N, McAinsh J, et al "Pharmacokinetics of atenolol in patients with renal impairment." Eur J Pharmacol 12 (1977): 175-80
Wan SH, Koda RT, Maronde RF "Pharmacokinetics, pharmacology of atenolol and effect of renal disease." Br J Clin Pharmacol 7 (1979): 569-74
McAinsh J, Holmes BF, Smith S, Hood D, Warren D "Atenolol kinetics in renal failure." Clin Pharmacol Ther 28 (1980): 302-9
Kirch W, Schafer M, Braun M "Single intravenous dose kinetics and accumulation of atenolol in patients with impaired renal function and on hemodialysis." Arch Toxicol Suppl 4 (1980): 366-9
Kotegawa T, Fujimura A, Ebihara A "Clinical pharmacology of dilevalol (IV): influence of hepatic and renal functions on the disposition of dilevalol and atenolol in hypertensive subjects." J Clin Pharmacol 30 (1990): 404-8

Atenolol and chlorthalidone

Generic Name: atenolol / chlorthalidone

Brand Name: Tenoretic 100, Tenoretic 50, Tenoretic

Synonyms: Atenolol and Chlorthalidone

What is Atenolol and chlorthalidone?