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Somnote and Cardiac disease
Result of checking the interaction of drug Somnote and disease Cardiac disease for safety when used together.
Check result:
Somnote <> Cardiac disease
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Although continued use of chloral hydrate at therapeutic dosages has not been associated with deleterious effects on the heart, large doses may produce peripheral vasodilation, hypotension, arrhythmias, and myocardial depression. High dosages of chloral hydrate should be avoided in patients with severe cardiac disease.
References:
- Nordenberg A, Delisle G, Izukawa T "Cardiac arrhythmia in a child due to chloral hydrate ingestion." Pediatrics 47 (1971): 134-5
- Marshall AJ "Cardiac arrhythmias caused by chloral hydrate." Br Med J 2 (1977): 994
- American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
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