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Sinequan (Doxepin Oral Concentrate) and Depression

Result of checking the interaction of drug Sinequan (Doxepin Oral Concentrate) and disease Depression for safety when used together.

Check result:
Sinequan (Doxepin Oral Concentrate) <> Depression
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

A variety of abnormal thinking and behavior changes have been reported to occur in association with the use of most anxiolytics, sedatives and hypnotics. Some of these changes include decreased inhibition, aggressiveness, agitation, and hallucinations. These drugs can cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with these drugs should be administered cautiously in patients with a history of depression or other psychiatric disorders. Patients should be monitored for any changes in mood or behavior. It may be prudent to refrain from dispensing large quantities of medication to these patients.

References:
  • "Product Information. Ambien (zolpidem)." sanofi-aventis, Bridgewater, NJ.
  • "Product Information. Sonata (zaleplon)" Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • "Product Information. Equanil (meprobamate)." Wallace Laboratories, Cranbury, NJ.
  • "Product Information. Aquachloral Supprettes (chloral hydrate)." Medisca, Plattsburg, NY.
  • "Product Information. Placidyl (ethchlorvynol)." Abbott Pharmaceutical, Abbott Park, IL.
Sinequan (Doxepin Oral Concentrate)

Generic Name: doxepin

Brand Name: Sinequan, Sinequan, Silenor

Synonyms: Sinequan Capsules, Sinequan

Sinequan (Doxepin Oral Concentrate) <> Depression
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Adult and pediatric patients with depression may experience worsening of their symptoms and may have the emergence of suicidal thoughts and behavior. Patients should be monitored appropriately and observed closely for worsening of their symptoms, suicidality or changes in their behavior, especially during the first few months of treatment, and at times of dose changes. Families and caregivers should be advised of the need for close observation and communication with the treating physician. Discontinuing the medication should be considered if symptoms are persistently worse, or abrupt in onset. It may be prudent to refrain from dispensing large quantities of medication to these patients.

Sinequan (Doxepin Oral Concentrate)

Generic Name: doxepin

Brand Name: Sinequan, Sinequan, Silenor

Synonyms: Sinequan Capsules, Sinequan

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